Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | IL1B | P01584 | 13/20 | 0.52 |
| ▸ | TNF | P01375 | 2/20 | 0.43 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157075 | 1.00 | NLRP3 (0.72) | NLRP3KCNH2IL1BTNFTRPV3 | |
| SCHEMBL27224407 | 0.93 | NLRP3 (0.67) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL30156937 | 0.93 | NLRP3 (0.67) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL30157129 | 0.89 | NLRP3 (0.67) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL27224429 | 0.89 | NLRP3 (0.67) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL30157063 | 0.86 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFTRPV3 | |
| SCHEMBL26436802 | 0.86 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFTRPV3 | |
| SCHEMBL27224408 | 0.86 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFTRPV3 | |
| SCHEMBL26438471 | 0.86 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFTRPV3 | |
| SCHEMBL30932818 | 0.85 | NLRP3 (0.62) | NLRP3KCNH2IL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4375274-A1 | ANNULATED PYRIDAZINE COMPOUND | Nico Therapeutics, Inc. (US) | 2024-05-29 | — | — | EP | disclosed |