Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.65 |
| ▸ | ESRRA | P11474 | 5/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.62 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | ESRRB | O95718 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077464 | 0.94 | ESR1 (0.65) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL30635319 | 0.94 | ESR1 (0.65) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL21077468 | 0.94 | ESR1 (0.65) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL27339182 | 0.94 | ESR1 (0.65) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL3319051 | 0.92 | ESR1 (0.65) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL23388673 | 0.90 | ESR1 (0.63) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL23752638 | 0.90 | ESR1 (0.60) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL23752639 | 0.90 | ESR1 (0.60) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL23388674 | 0.90 | ESR1 (0.62) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL23752625 | 0.90 | ESR1 (0.62) | ESR1ESRRAESR2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174711-A1 | PROCESS FOR PREPARING B-[(7a, 1713)-17-HYDROXY-7-[9-[(4,4,5,5,5-PENTAFLUOROPENTYL)SULFINYL]NONYL]ESTRA-1,3,5(10)-TRIEN-3-YL]-BORONIC ACID | INDUSTRIALE CHIMICA S.R.L. (IT) | 2024-05-30 | — | — | US | claimed |
| US-20240174711-A1 | PROCESS FOR PREPARING B-[(7a, 1713)-17-HYDROXY-7-[9-[(4,4,5,5,5-PENTAFLUOROPENTYL)SULFINYL]NONYL]ESTRA-1,3,5(10)-TRIEN-3-YL]-BORONIC ACID | INDUSTRIALE CHIMICA S.R.L. (IT) | 2024-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174711-A1 | PROCESS FOR PREPARING B-[(7a, 1713)-17-HYDROXY-7-[9-[(4,4,5,5,5-PENTAFLUOROPENTYL)SULFINYL]NONYL]ESTRA-1,3,5(10)-TRIEN-3-YL]-BORONIC ACID | HSD17B11, CYP19A1, HSD17B7 | ESR1 7/4885ESRRA 28/4885ESR2 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.