Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.56 |
| ▸ | IDO1 | P14902 | 6/20 | 0.56 |
| ▸ | TDO2 | P48775 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30860846 | 1.00 | METAP2 (0.56) | METAP2IDO1TDO2CYP1A2CHEK1 | |
| SCHEMBL18714303 | 0.80 | METAP2 (0.58) | METAP2IDO1TDO2CYP1A2METTL3 | |
| SCHEMBL24455088 | 0.79 | METAP2 (0.56) | METAP2IDO1TDO2CYP1A2METTL3 | |
| SCHEMBL30858873 | 0.79 | METAP2 (0.56) | METAP2IDO1TDO2CYP1A2METTL3 | |
| SCHEMBL31200266 | 0.79 | METAP2 (0.56) | METAP2IDO1TDO2CYP1A2METTL3 | |
| SCHEMBL2009063 | 0.79 | METAP2 (0.56) | METAP2IDO1TDO2CYP1A2METTL3 | |
| SCHEMBL30861084 | 0.76 | IDO1 (0.61) | METAP2IDO1TDO2CYP1A2CHEK1 | |
| SCHEMBL304051 | 0.76 | IDO1 (0.61) | METAP2IDO1TDO2CYP1A2CHEK1 | |
| SCHEMBL30860807 | 0.75 | IDO1 (0.51) | METAP2IDO1TDO2CYP1A2CHEK1 | |
| SCHEMBL27228008 | 0.75 | IDO1 (0.51) | METAP2IDO1TDO2CYP1A2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174647-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. | 2024-05-30 | — | — | US | disclosed |
| WO-2024073073-A2 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174647-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | LRRK2, MAP3K20, MAP3K5 | METAP2 2877/4885IDO1 2631/4885TDO2 3302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.