Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27228589 | 0.86 | BUB1 (0.36) | BUB1USP2SMN1; SMN2CTSKGAA | |
| SCHEMBL24868488 | 0.85 | BUB1 (0.36) | BUB1USP2SMN1; SMN2CTSKGAA | |
| SCHEMBL20705097 | 0.82 | BUB1 (0.40) | BUB1USP2SMN1; SMN2CTSKGAA | |
| SCHEMBL22214352 | 0.82 | BUB1 (0.40) | BUB1USP2SMN1; SMN2CTSKGAA | |
| SCHEMBL25153468 | 0.80 | BUB1 (0.38) | BUB1USP2SMN1; SMN2CTSKGAA | |
| SCHEMBL16414303 | 0.80 | BUB1 (0.39) | BUB1USP2SMN1; SMN2CTSKGAA | |
| SCHEMBL21244820 | 0.79 | BUB1 (0.40) | BUB1USP2SMN1; SMN2CTSKGAA | |
| SCHEMBL27228228 | 0.77 | BUB1 (0.37) | BUB1USP2SMN1; SMN2CTSKCHRM2 | |
| SCHEMBL16468545 | 0.77 | CTSK (0.42) | BUB1USP2SMN1; SMN2CTSKCHRM2 | |
| SCHEMBL2796099 | 0.76 | BUB1 (0.39) | BUB1USP2SMN1; SMN2CTSKNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240173439-A1 | FLUORINE-CONTAINING COMPOUND AND CONTRAST MEDIUM | TDK CORPORATION (JP) | 2024-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240173439-A1 | FLUORINE-CONTAINING COMPOUND AND CONTRAST MEDIUM | AFF1, AFF2, AFF4 | BUB1 2562/4885USP2 3618/4885SMN1; SMN2 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.