Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 12/20 | 0.61 |
| ▸ | F13A1 | P00488 | 2/20 | 0.61 |
| ▸ | TGM1 | P22735 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.61 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38661653 | 1.00 | TGM2 (0.61) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL1381808 | 0.86 | TGM2 (0.65) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL23328326 | 0.83 | TGM2 (0.61) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL2723385 | 0.83 | TGM2 (0.61) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL439369 | 0.81 | TGM2 (0.79) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL38661397 | 0.81 | TGM2 (0.60) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL38664259 | 0.81 | TGM2 (0.60) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL10033524 | 0.80 | TSHR (0.60) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL2724911 | 0.79 | TGM2 (0.56) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL21787312 | 0.79 | TGM2 (0.65) | TGM2F13A1TGM1LMNATGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612392-A | N-substituted acrylamide and methacrylamide derivatives and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-16 | — | — | US | claimed |
| US-10023782-B2 | Salt-tolerant, thermally-stable rheology modifiers | ISP INVESTMENTS LLC (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170335162-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | HERCULES LLC | 2017-11-23 | — | — | US | disclosed |
| US-9611416-B2 | Salt-tolerant, thermally-stable rheology modifiers | ISP INVESTMENTS LLC (US) | 2017-04-04 | — | — | US | disclosed |
| US-20130324443-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | ISP INVESTMENTS INC. (US) | 2013-12-05 | — | — | US | disclosed |
| WO-2013162902-A1 | SYNERGISTIC COMBINATION OF A FLUID LOSS ADDITIVE AND RHEOLOGY MODIFIER | ISP INVESTMENTS INC (US) | 2013-10-31 | — | — | WO | disclosed |
| WO-2013138156-A1 | SYNTHESIS AND APPLICATION OF HIGH PRESSURE HIGH TEMPERATURE FLUID LOSS ADDITIVE AND RHEOLOGY STABILIZER | ISP INVESTMENTS INC. (US) | 2013-09-19 | — | — | WO | disclosed |
| WO-2012061147-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | ISP INVESTMENTS INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| US-4612392-A | N-substituted acrylamide and methacrylamide derivatives and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-16 | — | — | US | disclosed |
| EP-0087714-B1 | N-SUBSTITUTED (METH)-ACRYL AMIDE DERIVATIVES AND THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1984-12-05 | — | — | EP | disclosed |
| EP-0087714-A1 | N-Substituted (meth)-acryl amide derivatives and their preparation | BASF Aktiengesellschaft (DE) | 1983-09-07 | — | — | EP | disclosed |