SCHEMBL272334

SCHEMBL272334

O=[C]Cc1cccnc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5368313 0.83
SCHEMBL7462925 0.80 EPHX2 (0.58)
SCHEMBL348855 0.79 CHRNA7 (0.57)
SCHEMBL2560125 0.78
SCHEMBL3207879 0.78
SCHEMBL29493676 0.78
SCHEMBL4358547 0.78
SCHEMBL4575811 0.78
SCHEMBL254758 0.78
SCHEMBL1361794 0.78 NAPRT (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 410 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-118354781-A Peptide inhibitors of interleukin-23 receptor 西兰制药公司 2024-07-16 CN claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
WO-2023036707-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2023-03-16 WO claimed
CN-110036009-A Substituted pyrrolidines and their use in the treatment of cystic fibrosis 艾伯维公司 2019-07-19 CN claimed
CN-106432233-B The preparation method of N, N, 6- trimethyl -2- (4- aminomethyl phenyls) imidazo [1,2-a] pyridine -3- acetamides 华东理工大学 2018-08-14 CN claimed
CN-106432233-A Preparation method of N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-alpha]pyridine-3-acetamide 华东理工大学 2017-02-22 CN claimed
US-8329853-B2 Process for the preparation of poly-α-glutamic acid and derivatives thereof CELL THERAPEUTICS, INC. (US) 2012-12-11 US claimed
US-20120277164-A1 GADD45BETA TARGETING AGENTS IMPERIAL INNOVATIONS LIMITED (GB) 2012-11-01 US claimed
EP-2491051-A2 GADD45BETA TARGETING AGENTS Imperial Innovations Limited (GB) 2012-08-29 EP claimed
EP-0497835-A1 METHOD FOR TREATING HIV AND OTHER RETROVIRUSES AND COMPOUNDS USEFUL THEREFOR THE UPJOHN COMPANY (US) 1992-08-12 EP claimed
EP-0480918-A1 REDUCED SIZE LHRH ANALOGS ABBOTT LABORATORIES (US) 1992-04-22 EP claimed
EP-0480918-A4 REDUCED SIZE LHRH ANALOGS. ABBOTT LAB (US) 1991-06-04 EP claimed
WO-1991006561-A1 METHOD FOR TREATING HIV AND OTHER RETROVIRUSES AND COMPOUNDS USEFUL THEREFOR THE UPJOHN COMPANY (US) 1991-05-16 WO claimed
WO-1989007451-A1 REDUCED SIZE LHRH ANALOGS ABBOTT LABORATORIES (US) 1989-08-24 WO claimed
EP-0328089-A2 Reduced size LHRH analogs ABBOTT LABORATORIES (US) 1989-08-16 EP claimed
EP-0131995-B1 COMPOUNDS WITH HYPOLIPEMIC ACTIVITY MAGGIONI-WINTHROP S.P.A. (IT) 1988-02-03 EP claimed
US-4571401-A 3-Pyridine acetic and 3-(3-pyridyl-methoxycarbonyl)-propionic acid pantetheine and pantetheine esters having hypolipemic activities MAGGIONI FARMACEUTICI S.P.A. (IT) 1986-02-18 US claimed
EP-0131995-A1 Compounds with hypolipemic activity MAGGIONI-WINTHROP S.P.A. (IT) 1985-01-23 EP claimed
US-4401660-A TYLOSINS; VETERINARY MEDICINE; PASTEURELLA; ANIMAL GROWTH REGULATORS ELI LILLY AND COMPANY (US) 1983-08-30 US claimed