SCHEMBL254758

SCHEMBL254758

N#CCc1cccnc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29493676 1.00
Hydrochloric Acid SCHEMBL8844927 0.98 CYP1A2 (0.50)
Pyrrole SCHEMBL28319269 0.91 KMT2A (0.44)
SCHEMBL11065869 0.87 TBXAS1 (0.51)
Ethoxycarbonyl Group SCHEMBL27707875 0.81 KMT2A (0.44)
SCHEMBL255080 0.79 CHRNA7 (0.57)
SCHEMBL5368313 0.78
SCHEMBL2560125 0.78
SCHEMBL4575811 0.78
SCHEMBL272334 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1078 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113999201-B Synthesis and preparation method of nicotine 成昌梅 2023-11-03 CN claimed
CN-116425786-A Fluorescent probe for dual-channel detection of apoptosis, preparation method and application 安徽大学 2023-07-14 CN claimed
CN-116003313-A Preparation method and application of AIE fluorescent compound for rapidly monitoring ammonia gas 天津理工大学 2023-04-25 CN claimed
CN-115286615-A Preparation method of racemic nicotine 深圳市真味生物科技有限公司 2022-11-04 CN claimed
CN-110483381-B Preparation method and application of solid-state acid-base stimulation response near-infrared fluorescent compound 天津理工大学 2022-02-22 CN claimed
CN-113999201-A Synthetic preparation method of nicotine 成昌梅 2022-02-01 CN claimed
CN-110483381-A A kind of preparation method and application of the near infrared fluorescent compound of solid-state soda acid stimuli responsive UNIV TIANJIN TECHNOLOGY 2019-11-22 CN claimed
CN-105968094-B A kind of carbazoles fluorescence probe and its preparation method and application measuring ClO- 山西大学 2018-10-16 CN claimed
EP-3103437-B1 SKIN LIGHTENING COMPOSITIONS ELC MAN LLC (US) 2017-12-20 EP claimed
US-9469741-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2016-10-18 US claimed
EP-2203482-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS Bridgestone Corporation (JP) 2010-07-07 EP claimed
WO-2009076170-A2 COMBINATIONS OF THERAPEUTIC AGENTS FOR TREATING CANCER NOVARTIS AG (CH) 2009-06-18 WO claimed
WO-2009051702-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2009-04-23 WO claimed
WO-2009051700-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (US) 2009-04-23 WO claimed
US-20090099325-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION 2009-04-16 US claimed
CN-1821243-A Substituted pyridine M receptor excitomotor, its preparing process and its use UNIV BEIJING (CN) 2006-08-23 CN claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
EP-0113600-B1 GAMMA-BUTYROLACTONE DERIVATIVES WITH MYOCARDIUM PROTECTING AND ANTIARRHYTMIC ACTIVITY, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM SANOFI S.A. (FR) 1987-07-29 EP claimed