Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934219 | 0.81 | CA2 (0.47) | GBA1G6PDCA12CA2CA9 | |
| SCHEMBL10525500 | 0.79 | NPSR1 (0.40) | C5AR1NPSR1CYP24A1LMNAMAPK1 | |
| SCHEMBL13728257 | 0.79 | C5AR1 (0.35) | GBA1C5AR1G6PDCA12CA2 | |
| SCHEMBL13728254 | 0.79 | C5AR1 (0.35) | GBA1C5AR1G6PDCA12CA2 | |
| SCHEMBL8343813 | 0.79 | CA2 (0.42) | GBA1G6PDCA12CA2CA9 | |
| SCHEMBL19615017 | 0.78 | CA1 (0.44) | GBA1G6PDCA12CA2CA9 | |
| SCHEMBL28057839 | 0.78 | CA2 (0.44) | GBA1G6PDCA12CA2CA9 | |
| SCHEMBL11786748 | 0.78 | MCHR1 (0.42) | GBA1G6PDCA12CA2CA9 | |
| SCHEMBL16024444 | 0.77 | GBA1 (0.36) | GBA1C5AR1G6PDCA12CA2 | |
| SCHEMBL13830368 | 0.77 | C5AR1 (0.34) | GBA1C5AR1CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061805-A1 | EPOXIDE BASED LINKERS | VANDERBILT UNIVERSITY (US) | 2012-05-10 | — | — | WO | disclosed |