Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.53 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491121 | 0.78 | NFE2L2 (0.51) | NFE2L2JUNNFKB1CYP1A2CYP1A1 | |
| SCHEMBL6491117 | 0.78 | NFE2L2 (0.51) | NFE2L2JUNNFKB1CYP1A2CYP1A1 | |
| SCHEMBL14686325 | 0.77 | NPC1 (0.48) | NFE2L2JUNNFKB1CYP1A2CYP1A1 | |
| SCHEMBL4770742 | 0.77 | PPARG (0.53) | NFE2L2MAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL12324763 | 0.77 | PPARG (0.53) | NFE2L2MAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL863053 | 0.77 | PPARG (0.53) | NFE2L2MAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL24909548 | 0.76 | NFE2L2 (0.58) | NFE2L2JUNNFKB1ALOX5NPC1 | |
| SCHEMBL6609137 | 0.76 | PPARG (0.49) | KDM4EALDH1A1 | |
| SCHEMBL6609135 | 0.76 | PPARG (0.49) | KDM4EALDH1A1 | |
| SCHEMBL2130152 | 0.74 | NFE2L2 (0.53) | NFE2L2CYP1A2ALOX5NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332900-B | Olefin compound and synthesis method thereof | 华中科技大学 | 2024-12-06 | — | — | CN | disclosed |
| US-20240180158-A1 | COMPOUNDS HAVING SELECTIVE INACTIVATION ACTIVITY | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2024-06-06 | — | — | US | disclosed |
| CN-116332900-A | Olefin compound and synthesis method thereof | 华中科技大学 | 2023-06-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240180158-A1 | COMPOUNDS HAVING SELECTIVE INACTIVATION ACTIVITY | GAA, MGAM, GBA3 | NFE2L2 2626/4885JUN 2648/4885NFKB1 3260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.