Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | FFAR1 | O14842 | 15/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23386065 | 0.92 | POLB (0.65) | POLBFFAR1FFAR4 | |
| SCHEMBL30343673 | 0.89 | POLB (0.69) | POLBFFAR1FFAR4 | |
| SCHEMBL21317665 | 0.87 | POLB (1.00) | POLBFFAR1 | |
| SCHEMBL1924061 | 0.85 | POLB (0.56) | POLBFFAR1 | |
| SCHEMBL1142783 | 0.85 | HSD17B10 (0.63) | POLBFFAR4 | |
| SCHEMBL8619804 | 0.84 | FFAR1 (0.55) | POLBFFAR1FFAR4 | |
| SCHEMBL20244569 | 0.84 | POLB (0.55) | POLBFFAR1FFAR4 | |
| SCHEMBL20232560 | 0.83 | POLB (0.71) | POLBFFAR1 | |
| SCHEMBL490637 | 0.83 | POLB (0.71) | POLBFFAR1 | |
| SCHEMBL25648716 | 0.83 | POLB (0.71) | POLBFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777477-B | Method for synthesizing succinic acid derivative or 3-aryl propionic acid | 四川大学 | 2021-09-14 | — | — | CN | disclosed |
| CN-111777477-A | Method for synthesizing succinic acid derivative or 3-aryl propionic acid | 四川大学 | 2020-10-16 | — | — | CN | disclosed |
| EP-2632269-A1 | CYCLIC AMINE SUBSTITUTED OXAZOLIDINONE CETP INHIBITOR | Merck Sharp & Dohme Corp. (US) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012058187-A1 | CYCLIC AMINE SUBSTITUTED OXAZOLIDINONE CETP INHIBITOR | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | disclosed |
| EP-2253315-A1 | Alkoxyphenylpropanoic acid derivatives | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | disclosed |
| US-20070197594-A1 | Cyclic amine derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2007-08-23 | — | — | US | disclosed |
| US-20070197594-A1 | Cyclic amine derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2007-08-23 | — | — | US | disclosed |
| EP-1795524-A1 | CYCLIC AMINE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2007-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197594-A1 | Cyclic amine derivative or salt thereof | GRIN1, PARK7, GRIN3A | POLB 1383/4885FFAR1 3299/4885FFAR4 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.