SCHEMBL27240

SCHEMBL27240

CC(=O)OC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.45
NAAA Q02083 1/20 0.44
CYP19A1 P11511 4/20 0.42
CYP17A1 P05093 3/20 0.40
EPHX1 P07099 2/20 0.38
GLA P06280 1/20 0.38
EPHX2 P34913 2/20 0.38
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
SCN1A P35498 1/20 0.37
SCN2A Q99250 1/20 0.37
SCN3A Q9NY46 1/20 0.37
DPP4 P27487 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27814098 0.98 NPSR1 (0.43) NPSR1NAAACYP19A1CYP17A1EPHX1
SCHEMBL5608309 0.86 DPP4 (0.43) NPSR1NAAAALDH1A1DPP4
SCHEMBL12093413 0.84 NAAA (0.38) NPSR1NAAACYP19A1CYP17A1EPHX2
SCHEMBL231596 0.82 NPSR1 (0.56) NPSR1NAAACYP19A1CYP17A1EPHX2
SCHEMBL15145523 0.82 NAAA (0.34) NPSR1NAAACYP19A1CYP17A1EPHX2
SCHEMBL8395205 0.82 NAAA (0.45) NPSR1NAAACYP19A1CYP17A1EPHX1
Hydrochloric Acid SCHEMBL27869489 0.81 NAAA (0.33) NPSR1NAAACYP19A1CYP17A1EPHX1
SCHEMBL5607557 0.81 EP300 (0.35) NPSR1NAAADPP4
SCHEMBL865315 0.80 NPSR1 (0.48) NPSR1NAAACYP19A1CYP17A1EPHX1
SCHEMBL27736443 0.80 CYP19A1 (0.44) NPSR1NAAACYP19A1CYP17A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14445 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823115-B Compound for degrading Pol theta based on hydrophobic tag and preparation method and application thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2026-05-26 CN claimed
WO-2026090085-A1 TREATMENT OF CD33 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2026-04-30 WO claimed
US-12565653-B2 ATAXIN3 (ATXN3) RNAi agent compositions and methods of use thereof ALNYLAM PHARMACEUTICALS, INC. (US) 2026-03-03 US claimed
US-12553053-B2 Transmembrane serine protease 2 (TMPRSS2) iRNA compositions and methods of use thereof ALNYLAM PHARMACEUTICALS, INC. (US) 2026-02-17 US claimed
US-12534731-B2 Alpha-2A adrenergic receptor (ADRA2A) iRNA agent compositions and methods of use thereof ALNYLAM PHARMACEUTICALS, INC. (US) 2026-01-27 US claimed
EP-4627082-A1 TREATMENT OF MTRES1 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2025-10-08 EP claimed
US-20250283079-A1 ACTIN-BINDING LIM PROTEIN 3 (ABLIM3) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF ALNYLAM PHARMACEUTICALS, INC. (US) 2025-09-11 US claimed
US-12391945-B2 Coronavirus IRNA compositions and methods of use thereof ALNYLAM PHARMACEUTICALS, INC. (US) 2025-08-19 US claimed
EP-4594492-A1 MODIFIED DOUBLE-STRANDED RNA AGENTS Alnylam Pharmaceuticals, Inc. (US) 2025-08-06 EP claimed
US-12378553-B2 Modified double-stranded RNA agents ALNYLAM PHARMACEUTICALS, INC. (US) 2025-08-05 US claimed
US-6319906-B1 FOR THERAPY OF AUTOIMMUNE DISEASE, INFLAMMATORY DISEASE, FOR INHIBITING ALLOGRAFT REJECTION ISIS PHARMACEUTICALS 2001-11-20 US claimed
US-6312900-B1 FOR MODULATING METASTASIS OF MALIGNANT TUMORS VIA MODULATION OF ACTIVATING PROTEIN 1 ISIS PHARMACEUTICALS, INC. 2001-11-06 US claimed
JP-2000507833-A 2000-06-27 JP claimed
US-6077833-A FOR DIAGNOSIS, PREVENTION AND TREATMENT OF IMMUNE STATES AND DISORDERS AMENABLE TO TREATMENT THROUGH MODULATION OF T CELL ACTIVATION SUCH AS FOR PREVENTING ALLOGRAFT REJECTION ISIS PHARMACEUTICALS, INC. (US) 2000-06-20 US claimed
US-6001991-A NUCLEOTIDE SEQUENCES WHICH HYBRIDIZE TO AND SUPPRESS EXPRESSION OF MULTIDRUG RESISTANCE GENE; FOR PREVENTING OR MODULATING THE DEVELOPMENT OF MULTIDRUG RESISTANCE DURING CHEMOTHERAPEUTIC TREATMENT OR RESENSITIZING TREATED CELLS ISIS PHARMACEUTICALS INC. (US) 1999-12-14 US claimed
EP-0957926-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS FOR THE MODULATION OF THE EXPRESSION OF B7 PROTEIN ISIS PHARMACEUTICALS, INC. (US) 1999-11-24 EP claimed
WO-1998029124-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS FOR THE MODULATION OF THE EXPRESSION OF B7 PROTEIN ISIS PHARMACEUTICALS, INC. (US) 1998-07-09 WO claimed
WO-1998014615-A1 ANTISENSE OLIGONUCLEOTIDE MODULATION OF MDR P-GLYCOPROTEIN GENE EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 1998-04-09 WO claimed
EP-0358574-B1 PROCESS FOR THE PREPARATION OF ADAMANTANE-1 DERIVATIVES CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) 1993-02-17 EP claimed
US-5015758-A Process for the preparation of 1-adamantane derivatives CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) 1991-05-14 US claimed