Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532479 | 0.77 | GPR119 (0.45) | GPR119 | |
| SCHEMBL1071669 | 0.76 | GPR119 (0.58) | GPR119CYP2C9KCNH2 | |
| SCHEMBL15253092 | 0.72 | GPR119 (0.37) | GPR119 | |
| SCHEMBL15253185 | 0.71 | GPR119 (0.44) | GPR119 | |
| SCHEMBL299567 | 0.71 | GPR119 (0.39) | GPR119 | |
| SCHEMBL299568 | 0.71 | GPR119 (0.39) | GPR119 | |
| SCHEMBL4483371 | 0.71 | GPR119 (0.84) | GPR119CYP2C9 | |
| SCHEMBL288499 | 0.70 | GPR119 (0.41) | GPR119CYP2C9KCNH2 | |
| SCHEMBL3244099 | 0.70 | GPR119 (0.70) | GPR119CYP2C9 | |
| SCHEMBL288167 | 0.70 | GPR119 (0.70) | GPR119CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025811-A1 | INDOLYLPYRIMIDINES AS MODULATORS OF GPR119 | LUPIN LIMITED (IN) | 2012-03-01 | — | — | WO | disclosed |