SCHEMBL27240479

SCHEMBL27240479

CC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.39
P2RX7 Q99572 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27240472 1.00 MAPK1 (0.39) MAPK1P2RX7
SCHEMBL2877547 0.89 MAPK1 (0.39) MAPK1P2RX7
SCHEMBL27240680 0.89 MAPK1 (0.39) MAPK1P2RX7
SCHEMBL26697717 0.89 MAPK1 (0.39) MAPK1P2RX7
SCHEMBL24186458 0.83 USP30 (0.38) MAPK1P2RX7
SCHEMBL20442937 0.83 USP30 (0.38) MAPK1P2RX7
SCHEMBL21326425 0.83 USP30 (0.38) MAPK1P2RX7
SCHEMBL275602 0.75 MAPK1 (0.37) MAPK1P2RX7
SCHEMBL27240314 0.74 MAPK1 (0.39) MAPK1P2RX7
SCHEMBL27240308 0.74 MAPK1 (0.39) MAPK1P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190868-A1 SOS1 INHIBITORS ACERAND THERAPEUTICS (HONG KONG) LIMITED (HK) 2024-06-13 US disclosed
WO-2024102952-A1 SOS1 INHIBITORS ACERAND THERAPEUTICS (USA) LIMITED (US) 2024-05-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240190868-A1 SOS1 INHIBITORS SOS1, SOS2, SOST MAPK1 68/4885P2RX7 3389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.