Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CCR5 | P51681 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482861 | 0.87 | HTT (0.65) | HTTACHESMN1; SMN2LMNACCR5 | |
| SCHEMBL157266 | 0.83 | HTT (0.63) | HTTACHESMN1; SMN2LMNACCR5 | |
| SCHEMBL7141111 | 0.83 | HTT (0.63) | HTTACHESMN1; SMN2LMNACCR5 | |
| SCHEMBL8303697 | 0.81 | HTT (0.61) | HTTACHESMN1; SMN2LMNACCR5 | |
| Bicarbonate SCHEMBL7274222 | 0.77 | HTT (0.55) | HTTACHESMN1; SMN2LMNACCR5 | |
| SCHEMBL28705768 | 0.76 | HTT (0.53) | HTTACHESMN1; SMN2LMNAMEN1 | |
| SCHEMBL27687018 | 0.76 | HTT (0.52) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20218939 | 0.76 | CNR2 (0.75) | HTTACHESMN1; SMN2LMNACNR2 | |
| SCHEMBL20210693 | 0.76 | CNR2 (0.57) | HTTACHESMN1; SMN2LMNACNR2 | |
| SCHEMBL19423435 | 0.75 | HTT (0.51) | HTTACHESMN1; SMN2LMNACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789042-B1 | 1-ALKOXY 1H-IMIDAZO RING SYSTEMS AND METHODS | 3M INNOVATIVE PROPERTIES CO (US) | 2012-05-02 | — | — | EP | disclosed |