SCHEMBL27241663

SCHEMBL27241663

Clc1cccc(-n2cnc3ccccc32)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 6/20 1.00
HTT P42858 1/20 0.66
HCAR1 Q9BXC0 1/20 0.57
HPGD P15428 3/20 0.55
ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29830083 1.00 FGFR1 (1.00) FGFR1HTTHCAR1HPGDALDH1A1
SCHEMBL2642001 0.91 FGFR1 (0.83) FGFR1HTTHCAR1HPGD
SCHEMBL3417304 0.88 HTT (0.78) FGFR1HTT
SCHEMBL24119935 0.81 FGFR1 (0.69) FGFR1HTT
SCHEMBL28824918 0.81 HTT (0.72) FGFR1HTT
SCHEMBL29949104 0.81 FGFR1 (0.68) FGFR1HTT
SCHEMBL28848729 0.81 FGFR1 (0.68) FGFR1HTT
SCHEMBL8186581 0.80 FGFR1 (0.67) FGFR1HTT
SCHEMBL4015486 0.80 HTT (0.71) FGFR1HTT
SCHEMBL22780759 0.80 FGFR1 (0.67) FGFR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190901-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240190901-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 FGFR1 3788/4885HTT 971/4885HCAR1 4442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.