Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.83 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29830083 | 0.91 | FGFR1 (1.00) | FGFR1HTTHCAR1HPGD | |
| SCHEMBL27241663 | 0.91 | FGFR1 (1.00) | FGFR1HTTHCAR1HPGD | |
| SCHEMBL4015486 | 0.88 | HTT (0.71) | FGFR1HTT | |
| SCHEMBL2642019 | 0.82 | FGFR1 (0.60) | FGFR1HTT | |
| SCHEMBL16158540 | 0.82 | FGFR1 (0.83) | FGFR1HTT | |
| SCHEMBL3417304 | 0.82 | HTT (0.78) | FGFR1HTT | |
| SCHEMBL2641988 | 0.81 | FGFR1 (0.59) | FGFR1HTT | |
| SCHEMBL16158486 | 0.81 | FGFR1 (0.59) | FGFR1HTT | |
| SCHEMBL13045092 | 0.80 | FGFR1 (0.57) | FGFR1HTT | |
| SCHEMBL20180561 | 0.80 | HTT (0.59) | FGFR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | claimed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | claimed |
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| US-5360809-A | Imidazole compounds and their use as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-11-01 | — | — | US | disclosed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | disclosed |