Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1508587 | 1.00 | — | — | |
| Bicarbonate SCHEMBL4876554 | 0.95 | — | — | |
| Bicarbonate SCHEMBL28108456 | 0.95 | — | — | |
| Bicarbonate SCHEMBL28117635 | 0.95 | CA4 (0.50) | — | |
| Bicarbonate SCHEMBL28453637 | 0.95 | — | — | |
| Bicarbonate SCHEMBL11671974 | 0.95 | — | — | |
| Bicarbonate SCHEMBL16893405 | 0.95 | — | — | |
| Bicarbonate SCHEMBL29047103 | 0.95 | — | — | |
| Bicarbonate SCHEMBL10975165 | 0.95 | CA4 (0.50) | — | |
| Bicarbonate SCHEMBL28304971 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240194304-A1 | Prediction Method, Prediction Device, and Prediction Program for New Indication of Desired Known Drug or Equivalent Material Thereof | KARYDO THERAPEUTIX, INC. (JP) | 2024-06-13 | — | — | US | disclosed |