Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28304971 | 1.00 | — | — | |
| Bicarbonate SCHEMBL5493709 | 0.95 | CA4 (0.55) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL27148837 | 0.95 | CA4 (0.55) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL27241908 | 0.95 | — | — | |
| Bicarbonate SCHEMBL10901679 | 0.95 | — | — | |
| Bicarbonate SCHEMBL1508587 | 0.95 | — | — | |
| Bicarbonate SCHEMBL10975165 | 0.90 | CA4 (0.50) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL28453637 | 0.90 | — | — | |
| Bicarbonate SCHEMBL4876554 | 0.90 | — | — | |
| Bicarbonate SCHEMBL29047103 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106219587-B | The device of calcium chloride is prepared in the waste water of self-contained calcium chloride | 深圳市瑞升华科技股份有限公司 | 2017-12-12 | — | — | CN | disclosed |
| CN-206069401-U | The device of calcium chloride is prepared in the waste water of self-contained calcium chloride | 深圳市瑞升华科技股份有限公司 | 2017-04-05 | — | — | CN | disclosed |
| CN-106219587-A | The waste water of self-contained calcium chloride is prepared the device of calcium chloride | 深圳市瑞升华科技股份有限公司 | 2016-12-14 | — | — | CN | disclosed |