Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27242584 | 0.95 | ROCK1 (0.49) | SCN10AROCK2ROCK1CA1CA2 | |
| SCHEMBL27242530 | 0.92 | PTGER4 (0.51) | SCN10AROCK2ROCK1CA1CA2 | |
| SCHEMBL27242579 | 0.91 | PTGER4 (0.55) | SCN10AROCK2ROCK1CA1CA2 | |
| SCHEMBL30895659 | 0.90 | IDH1 (0.49) | SCN10AROCK2ROCK1ALDH1A1KDM4E | |
| SCHEMBL27242495 | 0.88 | CA1 (0.45) | SCN10AROCK2ROCK1CA1CA2 | |
| SCHEMBL27242479 | 0.87 | ALDH1A1 (0.44) | SCN10AROCK2ROCK1CA1CA2 | |
| SCHEMBL27242575 | 0.87 | SCN10A (0.46) | SCN10AROCK2ROCK1CA1CA2 | |
| SCHEMBL27242503 | 0.87 | SCN10A (0.46) | SCN10ACA1CA2CA12CA9 | |
| SCHEMBL30895664 | 0.86 | KDM4E (0.42) | SCN10ACA1CA2CA12CA9 | |
| SCHEMBL30895722 | 0.86 | MAPT (0.46) | SCN10AROCK2ROCK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4385980-A1 | INDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | disclosed |