Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Styrene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.48 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL1955286 | 1.00 | ALDH1A1 (0.78) | ALDH1A1TSHRHDAC3HDAC4HDAC1 | |
| Styrene SCHEMBL9328290 | 0.97 | ALDH1A1 (0.74) | ALDH1A1TSHRHDAC3HDAC4HDAC1 | |
| Styrene SCHEMBL9328301 | 0.97 | ALDH1A1 (0.74) | ALDH1A1TSHRHDAC3HDAC4HDAC1 | |
| Styrene SCHEMBL9011439 | 0.97 | ALDH1A1 (0.74) | ALDH1A1TSHRHDAC3HDAC4HDAC1 | |
| Styrene SCHEMBL17180460 | 0.95 | ALDH1A1 (0.70) | ALDH1A1TSHRHDAC3HDAC4HDAC1 | |
| Styrene SCHEMBL14660282 | 0.93 | ALDH1A1 (0.67) | ALDH1A1TSHRHDAC3HDAC4HDAC1 | |
| Styrene SCHEMBL27529933 | 0.93 | ALDH1A1 (0.67) | ALDH1A1TSHRHDAC3HDAC4HDAC1 | |
| Styrene SCHEMBL10707502 | 0.93 | ALDH1A1 (0.67) | ALDH1A1TSHRHDAC3HDAC4HDAC1 | |
| Styrene SCHEMBL15421310 | 0.92 | ALDH1A1 (0.74) | ALDH1A1TSHRHDAC3HDAC4HDAC1 | |
| Styrene SCHEMBL4259704 | 0.91 | ALDH1A1 (0.93) | ALDH1A1TSHRHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2534 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637627-B2 | Formulations and methods to remove non-acidic sulfur compounds from gas streams | BAKER HUGHES OILFIELD OPERATIONS LLC (US) | 2026-05-26 | — | — | US | claimed |
| WO-2026099899-A1 | AMINE FUNCTIONALIZED SILICA CATALYST FOR PREPARATION OF ORGANIC CARBONATE AND OTHER APPLICATIONS THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2026-05-15 | — | — | WO | claimed |
| CN-116920848-B | Fe (Fe)2O3/NiFe2O4Preparation method and application of composite metal oxide catalyst | 扬州大学 | 2025-06-24 | — | — | CN | claimed |
| WO-2025110454-A1 | METHOD FOR RECYCLING WASTE SECONDARY BATTERY ELECTRODE MATERIAL | 한국에너지기술연구원 | 2025-05-30 | — | — | WO | claimed |
| WO-2025090644-A1 | ORGANIC CARBONATES FOR CARBON CAPTURE, UTILIZATION, STORAGE, AND TRANSPORTATION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-05-01 | — | — | WO | claimed |
| EP-3949000-B1 | LITHIUM BATTERY COMPRISING A UREA-BASED COMPOUND AS ELECTROLYTE ADDITIVE | BAYERISCHE MOTOREN WERKE AG (DE) | 2025-04-30 | — | — | EP | claimed |
| US-20250115816-A1 | FORMULATIONS AND METHODS TO REMOVE NON-ACIDIC SULFUR COMPOUNDS FROM GAS STREAMS | BAKER HUGHES OILFIELD OPERATIONS LLC (US) | 2025-04-10 | — | — | US | claimed |
| CN-119786725-A | Secondary battery and preparation method thereof, and electric equipment | 厦门海辰储能科技股份有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-119619352-A | Method for determining content of ester solvent and additive in sodium ion battery electrolyte by GC-MS | 苏州新泊地分析测试技术有限公司 | 2025-03-14 | — | — | CN | claimed |
| WO-2025036795-A1 | SHAPE-MEMORY POLYMER | UNIVERSITEIT MAASTRICHT (NL) | 2025-02-20 | — | — | WO | claimed |
| US-5698731-A | REACTING ALKYL CARBONATE AND AROMATIC AMINES IN PRESENCE OF CARBAMATION CATALYST SELECTED FROM N,N-DISUBSTITUTED CARBAMATE COMPLEXS OF ZINC OR COPPER | Ministero Dell `Universita` e Della Ricerca Scientifica e Tecnologica (IT) | 1997-12-16 | — | — | US | claimed |
| US-5688988-A | REACTION OF AN ORGANIC CARBONATE WITH AROMATIC AMINE USING A ZINC AND/OR COPPER CARBONATE HYDROXIDE CATALYST | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1997-11-18 | — | — | US | claimed |
| US-5679871-A | Hydroxyalklylation of phenols | REICHHOLD CHEMICALS, INC. (US) | 1997-10-21 | — | — | US | claimed |
| EP-0767215-A1 | AROMATIC POLYCARBONATE-STYRENE POLYMER RESIN COMPOSITION | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-04-09 | — | — | EP | claimed |
| CN-1144531-A | Aromatic polycarbonate-styrene polymer resin composition | ASAHI CHEMICAL IND (JP) | 1997-03-05 | — | — | CN | claimed |
| EP-0752414-A1 | Process for the production of aromatic urethanes | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1997-01-08 | — | — | EP | claimed |
| EP-0752413-A1 | Process for the production of aromatic carbamates | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1997-01-08 | — | — | EP | claimed |
| US-4310707-A | Sodium stannate catalyst for hydroxyalkylation of phenols or thiophenols | THE DOW CHEMICAL COMPANY (US) | 1982-01-12 | — | — | US | claimed |
| US-4310708-A | Phosphonium catalysts for hydroxyalkylation of phenols or thiophenols | THE DOW CHEMICAL COMPANY (US) | 1982-01-12 | — | — | US | claimed |
| US-4310706-A | Imidazole catalysts for hydroxyalkylation of phenols or thiophenols | THE DOW CHEMICAL COMPANY (US) | 1982-01-12 | — | — | US | claimed |