⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3448681 | 0.87 | — | — | |
| SCHEMBL3412783 | 0.79 | — | — | |
| SCHEMBL4608727 | 0.77 | — | — | |
| SCHEMBL28645452 | 0.69 | — | — | |
| SCHEMBL13883148 | 0.69 | SIRT1 (0.33) | — | |
| SCHEMBL6634675 | 0.69 | MAPK1 (0.38) | — | |
| SCHEMBL29921534 | 0.67 | MEN1 (0.53) | — | |
| SCHEMBL27699874 | 0.67 | — | — | |
| SCHEMBL1669127 | 0.65 | — | — | |
| SCHEMBL8988873 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113727968-B | Process for preparing 4-oxo-pyrrolidine-3-carboxamide derivatives | 杏林制药株式会社 | 2024-08-23 | — | — | CN | claimed |
| CN-113727968-A | Process for preparing 4-oxopyrrolidine-3-carboxamide derivatives | 杏林制药株式会社 | 2021-11-30 | — | — | CN | claimed |
| WO-2020230802-A1 | METHOD FOR PRODUCING 4-OXOPYRROLIDINE-3-CARBOXAMIDE DERIVATIVES | 杏林製薬株式会社 | 2020-11-19 | — | — | WO | claimed |
| US-9108915-B2 | Method for producing 3,4-disubstituted pyrrolidine derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2015-08-18 | — | — | US | claimed |
| EP-2634172-A1 | METHOD FOR PRODUCING 3,4-DISUBSTITUTED PYRROLIDINE DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2013-09-04 | — | — | EP | claimed |
| US-20130217893-A1 | METHOD FOR PRODUCING 3,4-DISUBSTITUTED PYRROLIDINE DERIVATIVE | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2013-08-22 | — | — | US | claimed |
| CN-113727968-B | Process for preparing 4-oxo-pyrrolidine-3-carboxamide derivatives | 杏林制药株式会社 | 2024-08-23 | — | — | CN | disclosed |
| CN-113727968-B | Process for preparing 4-oxo-pyrrolidine-3-carboxamide derivatives | 杏林制药株式会社 | 2024-08-23 | — | — | CN | disclosed |
| CN-113727968-B | Process for preparing 4-oxo-pyrrolidine-3-carboxamide derivatives | 杏林制药株式会社 | 2024-08-23 | — | — | CN | disclosed |
| CN-113727968-A | Process for preparing 4-oxopyrrolidine-3-carboxamide derivatives | 杏林制药株式会社 | 2021-11-30 | — | — | CN | disclosed |
| CN-113727968-A | Process for preparing 4-oxopyrrolidine-3-carboxamide derivatives | 杏林制药株式会社 | 2021-11-30 | — | — | CN | disclosed |
| CN-113727968-A | Process for preparing 4-oxopyrrolidine-3-carboxamide derivatives | 杏林制药株式会社 | 2021-11-30 | — | — | CN | disclosed |
| WO-2020230802-A1 | METHOD FOR PRODUCING 4-OXOPYRROLIDINE-3-CARBOXAMIDE DERIVATIVES | 杏林製薬株式会社 | 2020-11-19 | — | — | WO | disclosed |
| EP-2634172-A4 | METHOD FOR PRODUCING 3,4-DISUBSTITUTED PYRROLIDINE DERIVATIVE | KYORIN SEIYAKU KK (JP) | 2014-01-29 | — | — | EP | disclosed |
| EP-2634172-A1 | METHOD FOR PRODUCING 3,4-DISUBSTITUTED PYRROLIDINE DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2013-09-04 | — | — | EP | disclosed |
| EP-2634172-A1 | METHOD FOR PRODUCING 3,4-DISUBSTITUTED PYRROLIDINE DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2013-09-04 | — | — | EP | disclosed |
| US-20130217893-A1 | METHOD FOR PRODUCING 3,4-DISUBSTITUTED PYRROLIDINE DERIVATIVE | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2013-08-22 | — | — | US | disclosed |
| US-20130217893-A1 | METHOD FOR PRODUCING 3,4-DISUBSTITUTED PYRROLIDINE DERIVATIVE | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2013-08-22 | — | — | US | disclosed |
| CN-103228628-A | Method for producing 3,4-disubstituted pyrrolidine derivative | KYORIN SEIYAKU KK | 2013-07-31 | — | — | CN | disclosed |
| WO-2012057093-A1 | METHOD FOR PRODUCING 3,4-DISUBSTITUTED PYRROLIDINE DERIVATIVE | 杏林製薬株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |