Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30890473 | 1.00 | GAA (0.33) | GAANPSR1AURKABACE1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL27244936 | 0.92 | KDM1A (0.32) | — | |
| SCHEMBL27245180 | 0.89 | GAA (0.35) | GAANPSR1BACE1ALDH1A1AKR1C3 | |
| SCHEMBL30890427 | 0.85 | BACE1 (0.48) | GAANPSR1BACE1ALDH1A1 | |
| SCHEMBL27245043 | 0.82 | BACE1 (0.39) | GAABACE1ALDH1A1ATM | |
| SCHEMBL27244746 | 0.82 | NPC1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL27245163 | 0.81 | BACE1 (0.39) | BACE1ALDH1A1 | |
| SCHEMBL30890499 | 0.75 | BACE1 (0.47) | AURKABACE1 | |
| SCHEMBL27244719 | 0.75 | BACE1 (0.47) | AURKABACE1 | |
| SCHEMBL27244855 | 0.74 | PTK2B (0.32) | GAANPSR1ALDH1A1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | EIF2AK2, ZC3HAV1, HAVCR2 | GAA 37/4885NPSR1 3523/4885AURKA 4391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.