SCHEMBL2724547

SCHEMBL2724547

COc1cc(F)c(-c2c3cccc(F)c3c(-c3c(F)c(F)c(C(F)(F)F)c(F)c3F)c3c(F)ccc(F)c23)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 1/20 0.33
CYP1A2 P05177 1/20 0.33
GRM7 Q14831 1/20 0.33
ENPP1 P22413 1/20 0.32
ALDH1A1 P00352 1/20 0.30
CDK2 P24941 1/20 0.30
MIF P14174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12086164 1.00 GRM8 (0.33) GRM8CYP1A2GRM7ENPP1ALDH1A1
SCHEMBL12086127 0.94 GRM8 (0.32) GRM8CYP1A2GRM7ENPP1
SCHEMBL2943542 0.94 GRM8 (0.32) GRM8CYP1A2GRM7ENPP1
SCHEMBL12086114 0.93 GRM8 (0.33) GRM8CYP1A2GRM7ENPP1ALDH1A1
SCHEMBL2728432 0.93 GRM8 (0.33) GRM8CYP1A2GRM7ENPP1ALDH1A1
SCHEMBL2712158 0.92 GRM8 (0.32) GRM8CYP1A2GRM7ENPP1
SCHEMBL12086104 0.92 GRM8 (0.32) GRM8CYP1A2GRM7ENPP1
SCHEMBL2940979 0.91 GRM8 (0.34) GRM8CYP1A2GRM7ENPP1CDK2
SCHEMBL2726247 0.90 ALDH1A1 (0.34) CYP1A2ALDH1A1CDK2MIF
SCHEMBL2727335 0.87 ALDH1A1 (0.37) CYP1A2ALDH1A1CDK2MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 EP disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 GRM8 4745/4885CYP1A2 22/4885GRM7 4674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.