Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 9/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 8/20 | 0.46 |
| ▸ | SLC2A3 | P11169 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27248958 | 0.84 | ROCK2 (0.59) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL31173640 | 0.82 | SLC2A1 (0.51) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL27248850 | 0.82 | SLC2A1 (0.51) | ROCK2ROCK1SLC2A1SLC2A3 | |
| SCHEMBL27248597 | 0.81 | MEN1 (0.63) | ROCK2ROCK1SLC2A1SLC2A3LMNA | |
| SCHEMBL27248985 | 0.79 | SLC2A1 (0.49) | ROCK2ROCK1SLC2A1SLC2A3CLK4 | |
| SCHEMBL31173546 | 0.79 | SLC2A1 (0.49) | ROCK2ROCK1SLC2A1SLC2A3CLK4 | |
| SCHEMBL27249103 | 0.79 | ROCK2 (0.57) | ROCK2ROCK1SLC2A1SLC2A3NPC1 | |
| SCHEMBL31173524 | 0.78 | MEN1 (0.50) | ROCK2ROCK1SLC2A1SLC2A3CLK4 | |
| SCHEMBL27248507 | 0.78 | MEN1 (0.50) | ROCK2ROCK1SLC2A1SLC2A3CLK4 | |
| SCHEMBL27476498 | 0.78 | SLC2A1 (0.48) | ROCK2ROCK1SLC2A1SLC2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360085-A1 | Glucose Uptake Inhibitors | KADMON CORPORATION, LLC (US) | 2024-10-31 | — | — | US | disclosed |
| US-12030857-B2 | Glucose uptake inhibitors | KADMON CORPORATION, LLC (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030857-B2 | Glucose uptake inhibitors | KADMON CORPORATION, LLC (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030857-B2 | Glucose uptake inhibitors | KADMON CORPORATION, LLC (US) | 2024-07-09 | — | — | US | disclosed |
| US-20220363648-A1 | Glucose Uptake Inhibitors | KADMON CORPORATION, LLC | 2022-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030857-B2 | Glucose uptake inhibitors | SLC2A1, SLC2A4, SLC2A2 | ROCK2 3701/4885ROCK1 3618/4885SLC2A1 1/4885 |
| US-20220363648-A1 | Glucose Uptake Inhibitors | SLC2A1, SLC2A4, SLC2A2 | ROCK2 3701/4885ROCK1 3618/4885SLC2A1 1/4885 |
| US-20240360085-A1 | Glucose Uptake Inhibitors | SLC2A3, SLC2A1, SLC2A4 | ROCK2 3707/4885ROCK1 3577/4885SLC2A1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.