Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 4/20 | 0.77 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.77 |
| ▸ | CDK2 | P24941 | 4/20 | 0.77 |
| ▸ | CTSL | P07711 | 3/20 | 0.68 |
| ▸ | YTHDC1 | Q96MU7 | 6/20 | 0.62 |
| ▸ | CDK1 | P06493 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30747798 | 1.00 | CCNE2 (0.77) | CCNE2CCNE1CDK2CTSLYTHDC1 | |
| SCHEMBL17802614 | 0.96 | CTSL (0.75) | CCNE2CCNE1CDK2CTSLYTHDC1 | |
| SCHEMBL17815602 | 0.90 | CCNE2 (0.64) | CCNE2CCNE1CDK2CTSLYTHDC1 | |
| SCHEMBL6944109 | 0.90 | CCNE2 (0.76) | CCNE2CCNE1CDK2CTSLYTHDC1 | |
| SCHEMBL27249493 | 0.85 | CTSL (0.64) | CCNE2CCNE1CDK2CTSLCDK1 | |
| SCHEMBL1443236 | 0.84 | TDP1 (0.80) | CCNE2CCNE1CDK2CDK1TDP1 | |
| SCHEMBL30747819 | 0.84 | CTSL (0.62) | CCNE2CCNE1CDK2CTSLCDK1 | |
| SCHEMBL27249494 | 0.84 | CTSL (0.62) | CCNE2CCNE1CDK2CTSLCDK1 | |
| SCHEMBL5462682 | 0.83 | CTSL (0.59) | CCNE2CCNE1CDK2CTSLCDK1 | |
| SCHEMBL30747744 | 0.83 | CTSL (0.61) | CCNE2CCNE1CDK2CTSLCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024013205-A1 | PHOSPHORYLPURINONE COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2024-01-18 | — | — | WO | disclosed |