Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | NAE1 | Q13564 | 6/20 | 0.35 |
| ▸ | UBA3 | Q8TBC4 | 6/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23456000 | 0.92 | EGFR (0.41) | EGFRERBB3SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL27250614 | 0.85 | EGFR (0.49) | EGFRERBB3SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL27250616 | 0.85 | EGFR (0.49) | EGFRERBB3SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL22401411 | 0.83 | EGFR (0.44) | EGFRERBB3SMN1; SMN2NPC1ADORA3 | |
| SCHEMBL23456264 | 0.83 | EGFR (0.44) | EGFRERBB3SMN1; SMN2NPC1ADORA3 | |
| SCHEMBL30164347 | 0.78 | NAE1 (0.47) | EGFRERBB3SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL23456099 | 0.78 | NAE1 (0.47) | EGFRERBB3SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL23487982 | 0.75 | EGFR (0.42) | EGFRERBB3SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL27252043 | 0.74 | EGFR (0.47) | EGFRERBB3SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL30164164 | 0.72 | EGFR (0.38) | EGFRERBB3SMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209017-A1 | STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240209017-A1 | STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING | STING1, CGAS, MAVS | EGFR 1818/4885ERBB3 3787/4885SMN1; SMN2 1969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.