Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 5/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27254382 | 0.86 | MEN1 (0.45) | MAOBPYCR1DNM1ACHE | |
| SCHEMBL27254366 | 0.84 | MAOB (0.35) | MAOBPYCR1DNM1MAOAHDAC1 | |
| SCHEMBL8936036 | 0.81 | MAOB (0.38) | ALDH1A1SMN1; SMN2MAOBPYCR1MAOA | |
| SCHEMBL26550945 | 0.77 | MAOB (0.35) | MAOBPYCR1MAOAACHE | |
| SCHEMBL24029587 | 0.75 | MAOB (0.34) | MAOBPYCR1ACHE | |
| SCHEMBL873911 | 0.74 | DNM1 (0.55) | ALDH1A1SMN1; SMN2DNM1 | |
| SCHEMBL3250569 | 0.73 | TDP1 (0.45) | MAOBMAOA | |
| Hydrochloric Acid SCHEMBL1612682 | 0.72 | DNM1 (0.53) | ALDH1A1SMN1; SMN2DNM1 | |
| SCHEMBL4795813 | 0.72 | — | — | |
| SCHEMBL8936028 | 0.71 | MAOB (0.42) | MAOBPYCR1MAOATMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073486-A2 | PROBES AND METHODS TO IDENTIFY LIGANDABLE FATTY ACYLATION SITES FOR THERAPEUTIC TARGET IDENTIFICATION | THE GENERAL HOSPITAL CORPORATION (US) | 2024-04-04 | — | — | WO | disclosed |