Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942909 | 0.79 | AHR (0.54) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL27988235 | 0.74 | F2 (0.50) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL5134026 | 0.74 | AHR (0.52) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL31543700 | 0.73 | AHR (0.52) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL13230543 | 0.73 | AHR (0.47) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL2976878 | 0.72 | MAOB (0.51) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL19063316 | 0.72 | NPC1 (0.51) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL31543727 | 0.70 | AHR (0.44) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL2889663 | 0.69 | NPC1 (0.56) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL31543723 | 0.69 | AHR (0.43) | AHRNR4A2CYP2A6F7LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024080792-A1 | NOVEL HETEROBICYCLIC COMPOUND FOR INHIBITING YAP-TEAD INTERACTION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | HANMI PHARM. CO., LTD. (KR) | 2024-04-18 | — | — | WO | disclosed |