SCHEMBL2889663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4806892	0.79	MEN1 (0.54)	AHRNR4A2CYP2A6F7LTA4H
	SCHEMBL28061060	0.79	IDO1 (0.50)	MAOAMAOBSLC6A2SLC6A4SLC6A3
	SCHEMBL29336860	0.79	IMPDH2 (0.63)	NPC1AHRNR4A2CYP2A6F7
	SCHEMBL8869328	0.76	L3MBTL1 (0.50)	NPC1AHRTRPA1CA1CA2
	SCHEMBL29336862	0.76	F2 (0.65)	NPC1USP2GAAALOX15RAD51
	SCHEMBL2942909	0.75	AHR (0.54)	NPC1AHRTRPA1CA1CA2
	SCHEMBL6090445	0.74	TUBB4A (0.48)	NPC1AHRNR4A2CYP2A6F7
	SCHEMBL5134026	0.74	AHR (0.52)	NPC1AHRTRPA1CA1CA2
	SCHEMBL446619	0.72	NPC1 (1.00)	NPC1AHRTRPA1CA1CA2
	SCHEMBL21480346	0.72	PLA2G1B (0.61)	AHRMAOAMAOBMAPTPLA2G1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.