Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 4/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27255478 | 0.83 | PTK2 (0.42) | PTK2LCKKITSRCKDR | |
| SCHEMBL27255493 | 0.78 | PTPN11 (0.37) | PTK2TDP1NR3C1XDHPTPN11 | |
| SCHEMBL27255164 | 0.77 | KCNH2 (0.51) | PTK2LCKKITSRCKDR | |
| SCHEMBL31591370 | 0.77 | PTK2 (0.44) | PTK2LCKKITSRCKDR | |
| SCHEMBL14136858 | 0.77 | PTK2 (0.44) | PTK2LCKKITSRCKDR | |
| SCHEMBL27255485 | 0.77 | MAPT (0.43) | PTK2LCKKITSRCKDR | |
| SCHEMBL31591387 | 0.76 | ALOX15B (0.51) | PTK2CYP1A2CYP2C19 | |
| SCHEMBL27255475 | 0.76 | ALOX15B (0.51) | PTK2CYP1A2CYP2C19 | |
| SCHEMBL16167709 | 0.75 | PTK2 (0.46) | PTK2LCKKITSRCKDR | |
| SCHEMBL27255480 | 0.72 | PTK2 (0.40) | PTK2LCKKITSRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024080792-A1 | NOVEL HETEROBICYCLIC COMPOUND FOR INHIBITING YAP-TEAD INTERACTION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | HANMI PHARM. CO., LTD. (KR) | 2024-04-18 | — | — | WO | disclosed |