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Sugi Predict / Targets / ALOX15B

ALOX15B

Polyunsaturated fatty acid lipoxygenase ALOX15B · O15296 · ALOX15B on Sugi Atlas →

3,290 patent compounds predicted against ALOX15B, 2,371 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL571151 SCHEMBL571151 1.00 3/20
Aus-131 Aus-131 (SCHEMBL43647) 0.74 3/20
Aus-131 Aus-131 (SCHEMBL43648) 0.74 3/20
Aus-131 Aus-131 (SCHEMBL677723) 0.74 3/20
Aus-131 Aus-131 (SCHEMBL2002128) 0.74 3/20
SCHEMBL4405448 SCHEMBL4405448 0.72 3/20
SCHEMBL6274762 SCHEMBL6274762 0.71 3/20
SCHEMBL6765169 SCHEMBL6765169 0.67 3/20
SCHEMBL6769624 SCHEMBL6769624 0.62 3/20
SCHEMBL4360255 SCHEMBL4360255 0.61 3/20
Aus-131 Aus-131 (SCHEMBL936521) 0.58 3/20
SCHEMBL3355537 SCHEMBL3355537 0.57 3/20
SCHEMBL936495 SCHEMBL936495 0.56 3/20
SCHEMBL5622792 SCHEMBL5622792 0.55 3/20
SCHEMBL5637192 SCHEMBL5637192 0.54 3/20
SCHEMBL2742792 SCHEMBL2742792 0.54 3/20
Hildegardiol Hildegardiol (SCHEMBL572125) 0.53 3/20
SCHEMBL4366072 SCHEMBL4366072 0.52 3/20
SCHEMBL6843949 SCHEMBL6843949 0.52 3/20
SCHEMBL4265964 SCHEMBL4265964 0.51 3/20

Clinical trials — most relevant to ALOX15B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Predicting Response to Standardized Pediatric Colitis Therapy PHASE4COMPLETED
The Effect of Ticagrelor on 15-Epi-Lipoxin A4 and Inflammation PHASE4WITHDRAWN
Does Pioglitazone Increase the Production of 15-EPI-Lipoxin A4? PHASE4COMPLETED
Diet Rich in N-3 Polyunsaturated Fatty Acids in Renal Transplant Recipients PHASE4COMPLETED
Atorvastatin, Aspirin, Oxidative Stress, Coagulation and Platelet Activation Indexes PHASE4UNKNOWN
Obesity and Asthma: Nutrigenetic Response to Omega-3 Fatty Acids PHASE2/PHASE3COMPLETED
Aspirin for Uncontrolled Asthma PHASE3COMPLETED
Montelukast for Early Life Wheezing PHASE2/PHASE3COMPLETED
Chemoprevention Trial in Familial Adenomatous Polyposis (FAP) Coli Using EPA PHASE2/PHASE3COMPLETED
Anti Inflammatory and Analgesic Effect of Ginger Powder in Dental Pain Model PHASE2UNKNOWN
Acute Pseudophakic Cystoid Macular Edema Treatment Trial: Intravitreal Ranibizumab Versus Triamcinolone Acetonide PHASE1COMPLETED
Role of 12-lipoxygenase in Platelet Reactivity and Type 2 Diabetes Mellitus EARLY_PHASE1COMPLETED
Heart & Health Study nanCOMPLETED
Fish Oil to Prevent Asthma Exacerbations in Patients With ALOX5 Polymorphisms nanCOMPLETED
Fatty Acid Regulation of Platelet Function in Diabetes nanCOMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish) nanUNKNOWN
Lipidomics Screening of Anti-inflammatory Drugs and Drug Candidates in Vitro - Part A nanACTIVE_NOT_RECRUITING
Eicosanoid Lipids by Airway Cells During Infection With Human Rhinoviruses nanCOMPLETED
PLatelets Acetyl-CoA Carboxylase Phosphorylation State in SEPtic Shock nanCOMPLETED
Lipidomics Screening of Celecoxib in ex Vivo Human Whole Blood Assay - Part B nanCOMPLETED
Gender Differences and SNPs in Asthmatic Patients nanUNKNOWN
The Severe Asthma Research Program III-Boston Clinical Site nanCOMPLETED
Leukotrienes Pathway in Chinese Children With Sleep-disordered Breathing nanUNKNOWN
Maresin-1 and Resolvin-D1 Levels and Disease Activity in Ulcerative Colitis nanCOMPLETED
Study of the Arachidonate 5-Lipoxygenase Enzyme in Affecting the Risk for Coronary Heart Disease nanCOMPLETED
Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL). nanRECRUITING
Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study nanCOMPLETED
Comparison of Docosahexaenoic (DHA) Values in Patients With Polycystic Ovary Syndrome (PCOS) nanUNKNOWN
Investigation of Lipoxin A4, Annexin A1 and Interleukin-1 Beta Levels in Individuals With Periodontitis. nanCOMPLETED
Role of Metabolic Enzymes in Non-Melanoma Skin Cancer nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ALOX15B binder may also engage these)

ProteinNameSimilarity
O35936 — 1.000 O35936 →
Q8K4F2 — 1.000 Q8K4F2 →
D3ZKX9 — 0.997 D3ZKX9 →
O75342 — 0.996 O75342 →
Q9BYJ1 — 0.996 Q9BYJ1 →
O70582 — 0.994 O70582 →
Q9WV07 — 0.994 Q9WV07 →
Q02759 — 0.993 Q02759 →
P55249 — 0.993 P55249 →
P39654 — 0.991 P39654 →
P12530 — 0.990 P12530 →
Q2KMM4 — 0.987 Q2KMM4 →
P39655 — 0.987 P39655 →
F1LQ70 — 0.986 F1LQ70 →
D3ZQF9 — 0.985 D3ZQF9 →
P27479 — 0.985 P27479 →
P12527 — 0.981 P12527 →
ALOX15 Polyunsaturated fatty acid lipoxygenase ALOX15 0.981 landscape →
Q5RBE8 — 0.980 Q5RBE8 →
P16469 — 0.980 P16469 →
ALOX12 Polyunsaturated fatty acid lipoxygenase ALOX12 0.978 landscape →
P51399 — 0.977 P51399 →
P48999 — 0.977 P48999 →
Q8VDP3 — 0.976 Q8VDP3 →
ALOX5 Polyunsaturated fatty acid 5-lipoxygenase 0.976 landscape →
D3ZBP4 — 0.975 D3ZBP4 →
Q8TDZ2 — 0.974 Q8TDZ2 →
Q68DD2 — 0.974 Q68DD2 →
Q6IFT6 — 0.973 Q6IFT6 →
Q002B5 — 0.973 Q002B5 →