SCHEMBL2725560

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2724966	0.95	MEN1 (0.42)	MEN1ALDH1A1KMT2AMAOBKDM4E
	SCHEMBL2725350	0.91	MEN1 (0.38)	MEN1ALDH1A1KMT2AMAOBKDM4E
	SCHEMBL2725666	0.89	HSD17B10 (0.33)	NFE2L2
	SCHEMBL2712513	0.89	HSD17B10 (0.33)	NFE2L2
	SCHEMBL12086086	0.89	HSD17B10 (0.33)	NFE2L2
	SCHEMBL2939483	0.88	MAOB (0.42)	MEN1ALDH1A1KMT2AMAOBKDM4E
	SCHEMBL2727508	0.88	DHODH (0.39)	ALDH1A1CA1CA2MAP2K4
	SCHEMBL2725439	0.87	MEN1 (0.40)	MEN1ALDH1A1KMT2AMAOBKDM4E
	SCHEMBL2727154	0.87	ACHE (0.43)	ALDH1A1MAOBKDM4ECA1CA2
	SCHEMBL2941148	0.86	MEN1 (0.37)	MEN1ALDH1A1KMT2AMAOBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.