Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 8/20 | 0.31 |
| ▸ | CES1 | P23141 | 5/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866970 | 0.77 | — | — | |
| SCHEMBL9475171 | 0.74 | CES2 (0.34) | CES2 | |
| SCHEMBL20274342 | 0.70 | CES2 (0.31) | CES2 | |
| SCHEMBL16140002 | 0.70 | CES2 (0.68) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL20274338 | 0.70 | CES2 (0.31) | CES2 | |
| SCHEMBL20274364 | 0.69 | CES2 (0.30) | CES2 | |
| SCHEMBL9475649 | 0.67 | CES2 (0.33) | CES2 | |
| SCHEMBL9475654 | 0.67 | CES2 (0.33) | CES2 | |
| SCHEMBL22996536 | 0.67 | CES2 (0.32) | CES2 | |
| SCHEMBL19966359 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632901-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLE-4-CARBOXAMIDES | SOLVAY (BE) | 2018-09-12 | — | — | EP | disclosed |
| EP-3174857-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE-4-CARBOXAMIDES | Solvay SA (BE) | 2017-06-07 | — | — | EP | disclosed |
| WO-2016016298-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE-4-CARBOXAMIDES | SOLVAY SA (BE) | 2016-02-04 | — | — | WO | disclosed |
| EP-2980078-A1 | Process for the preparation of pyrazole-4-carboxamides | Solvay SA (BE) | 2016-02-03 | — | — | EP | disclosed |
| EP-2632901-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE-4-CARBOXAMIDES | SOLVAY SA (BE) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012055864-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE-4-CARBOXAMIDES | SOLVAY SA (BE) | 2012-05-03 | — | — | WO | disclosed |