Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | BRD2 | P25440 | 2/20 | 0.31 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30961134 | 1.00 | PDE10A (0.34) | PDE10AGRIN1GRIN2AGRIA2NR3C2 | |
| SCHEMBL951102 | 0.95 | NR3C2 (0.36) | PDE10AGRIN1GRIN2AGRIA2NR3C2 | |
| SCHEMBL27257407 | 0.88 | RAB9A (0.34) | NR3C2ELANE | |
| SCHEMBL12912164 | 0.85 | NR3C2 (0.38) | NR3C2ELANENPSR1 | |
| SCHEMBL27256211 | 0.85 | PDE10A (0.35) | PDE10ABRD4BRD2BRD3 | |
| SCHEMBL27256455 | 0.84 | PDE10A (0.36) | PDE10A | |
| SCHEMBL30961199 | 0.83 | PDE10A (0.34) | PDE10AELANE | |
| SCHEMBL27256388 | 0.83 | PDE10A (0.34) | PDE10AELANE | |
| SCHEMBL950600 | 0.82 | ELANE (0.34) | GRIN1GRIN2AELANE | |
| SCHEMBL951344 | 0.82 | STIM1 (0.34) | GRIN1GRIN2AGRIA2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133426-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS AND COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-27 | — | — | WO | disclosed |