SCHEMBL2725720

SCHEMBL2725720

C=C(CC(=O)OCCCS(=O)(=O)O)C(=O)OCCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
FAAH O00519 2/20 0.47
NAAA Q02083 3/20 0.46
RAD52 P43351 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
EPHX1 P07099 1/20 0.41
HTR2C P28335 1/20 0.39
DGKA P23743 1/20 0.39
EPHX2 P34913 1/20 0.39
ACHE P22303 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35501 0.90 TSHR (0.33) TSHRFAAH
SCHEMBL22615483 0.89 TSHR (0.50) TSHRFAAHNAAARAD52NPSR1
Potassium SCHEMBL30634935 0.88 TSHR (0.32) TSHR
SCHEMBL5415483 0.88 TSHR (0.32) TSHR
SCHEMBL15215933 0.88 TSHR (0.35) TSHRFAAHNAAARAD52NPSR1
SCHEMBL2793926 0.88 TSHR (0.32) TSHR
SCHEMBL15156604 0.88 TSHR (0.62) TSHRFAAHNAAARAD52NPSR1
SCHEMBL892067 0.88 TSHR (0.62) TSHRFAAHNAAARAD52NPSR1
SCHEMBL3138822 0.88 TSHR (0.62) TSHRFAAHNAAARAD52NPSR1
SCHEMBL1561906 0.88 TSHR (0.62) TSHRFAAHNAAARAD52NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7714064-B2 Controllable and rapid solubility rate of water-soluble polymeric films HARBIN LONGYI NEW MATERIAL TECHNOLOGY CO. LTD. (CN) 2010-05-11 US claimed
US-20080097029-A1 CONTROLLABLE AND RAPID SOLUBILITY RATE OF WATER-SOLUBLE POLYMERIC FILMS HARBIN LONGYI NEW MATERIAL TECHNOLOGY CO. LTD. (CN) 2008-04-24 US claimed
US-20040204543-A1 Controllable and rapid solubility rate of water-soluble polymeric films YANG THOMAS P (CA) 2004-10-14 US claimed
US-10113099-B2 High pressure high temperature (HPHT) aqueous drilling mud composition and process for preparing the same ISP INVESTMENTS LLC (US) 2018-10-30 US disclosed
US-10023782-B2 Salt-tolerant, thermally-stable rheology modifiers ISP INVESTMENTS LLC (US) 2018-07-17 US disclosed
US-20170335162-A1 SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS HERCULES LLC 2017-11-23 US disclosed
US-9611416-B2 Salt-tolerant, thermally-stable rheology modifiers ISP INVESTMENTS LLC (US) 2017-04-04 US disclosed
US-20150368538-A1 A NOVEL HIGH PRESSURE HIGH TEMPERATURE (HPHT) AQUEOUS DRILLING MUD COMPOSITION AND PROCESS FOR PREPARING THE SAME ISP INVESTMENTS INC. (US) 2015-12-24 US disclosed
WO-2014133824-A1 A NOVEL HIGH PRESSURE HIGH TEMPERATURE (HPHT) AQUEOUS DRILLING MUD COMPOSITION AND PROCESS FOR PREPARING THE SAME ISP INVESTMENTS INC. (US) 2014-09-04 WO disclosed
US-20130324443-A1 SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS ISP INVESTMENTS INC. (US) 2013-12-05 US disclosed
WO-2013162902-A1 SYNERGISTIC COMBINATION OF A FLUID LOSS ADDITIVE AND RHEOLOGY MODIFIER ISP INVESTMENTS INC (US) 2013-10-31 WO disclosed
WO-2013138156-A1 SYNTHESIS AND APPLICATION OF HIGH PRESSURE HIGH TEMPERATURE FLUID LOSS ADDITIVE AND RHEOLOGY STABILIZER ISP INVESTMENTS INC. (US) 2013-09-19 WO disclosed
WO-2012061147-A1 SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS ISP INVESTMENTS INC. (US) 2012-05-10 WO disclosed
US-7714064-B2 Controllable and rapid solubility rate of water-soluble polymeric films HARBIN LONGYI NEW MATERIAL TECHNOLOGY CO. LTD. (CN) 2010-05-11 US disclosed
US-20080097029-A1 CONTROLLABLE AND RAPID SOLUBILITY RATE OF WATER-SOLUBLE POLYMERIC FILMS HARBIN LONGYI NEW MATERIAL TECHNOLOGY CO. LTD. (CN) 2008-04-24 US disclosed
US-20040204543-A1 Controllable and rapid solubility rate of water-soluble polymeric films YANG THOMAS P (CA) 2004-10-14 US disclosed