SCHEMBL15215933

SCHEMBL15215933

C=C(CC(=O)OCCCCS(=O)(=O)O)C(=O)OCCCCS(=O)(=O)O

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
FAAH O00519 1/20 0.33
APP P05067 1/20 0.31
NAAA Q02083 1/20 0.31
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
RAD52 P43351 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35501 0.95 TSHR (0.33) TSHRFAAHAPPPOLBAPEX1
Potassium SCHEMBL30634935 0.93 TSHR (0.32) TSHRAPPPOLBAPEX1HTT
SCHEMBL5415483 0.93 TSHR (0.32) TSHRAPPPOLBAPEX1HTT
SCHEMBL2793926 0.93 TSHR (0.32) TSHRAPPPOLBAPEX1HTT
SCHEMBL2725720 0.88 TSHR (0.50) TSHRFAAHNAAARAD52NPSR1
SCHEMBL2723010 0.88
SCHEMBL3148488 0.81 ALOX15 (0.32) FAAHAPP
SCHEMBL35502 0.81 TSHR (0.33) TSHRAPPPOLBAPEX1HTT
SCHEMBL29125655 0.80 ALOX15 (0.32) APP
SCHEMBL1547901 0.79 TSHR (0.39) TSHRFAAHNAAAPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9760060-B2 Photopolymer formulations for producing holographic media having highly crosslinked matrix polymers COVESTRO DEUTSCHLAND AG (DE) 2017-09-12 US disclosed
US-9146456-B2 Photopolymer formulation for producing holographic media having highly crosslinked matrix polymers BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-09-29 US disclosed
US-20130224634-A1 PHOTOPOLYMER FORMULATION FOR PRODUCING HOLOGRAPHIC MEDIA HAVING HIGHLY CROSSLINKED MATRIX POLYMERS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-08-29 US disclosed