Biphenyl

Biphenyl

SCHEMBL27258263

O=COc1cccc(O)c1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 5/20 0.45
HSD17B2 P37059 5/20 0.45
CYP3A4 P08684 4/20 0.45
CYP2C9 P11712 2/20 0.45
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
DRD2 P14416 1/20 0.42
DRD4 P21917 1/20 0.42
ADRA1D P25100 1/20 0.42
ADRA1A P35348 1/20 0.42
ADRA1B P35368 1/20 0.42
DRD3 P35462 1/20 0.42
CCNB2 O95067 1/20 0.41
CDK1 P06493 1/20 0.41
CDK4 P11802 1/20 0.41
CCNB1 P14635 1/20 0.41
CCND1 P24385 1/20 0.41
CCNB3 Q8WWL7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL454730 0.93 CYP3A4 (0.47) CYP3A4ESR1ESR2DRD2DRD4
Phenol SCHEMBL28088385 0.93 CYP3A4 (0.47) CYP3A4ESR1ESR2DRD2DRD4
Phenol SCHEMBL359808 0.93 CYP3A4 (0.47) CYP3A4ESR1ESR2DRD2DRD4
SCHEMBL320511 0.91 CYP3A4 (0.52) CYP3A4ESR1ESR2DRD2DRD4
Methane SCHEMBL27756372 0.89 CYP3A4 (0.50) CYP3A4ESR1ESR2DRD2DRD4
Resorcinol SCHEMBL1715185 0.89 CYP3A4 (0.50) CYP3A4ESR1ESR2DRD2DRD4
SCHEMBL4463825 0.89 CYP3A4 (0.50) CYP3A4ESR1ESR2DRD2DRD4
Charcoal, Activated SCHEMBL3483629 0.89 CYP3A4 (0.50) CYP3A4ESR1ESR2DRD2DRD4
SCHEMBL28073121 0.89 CYP3A4 (0.50) CYP3A4ESR1ESR2DRD2DRD4
SCHEMBL28290002 0.89 CYP3A4 (0.50) CYP3A4ESR1ESR2DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1098428-A The China ink that is used for ink-jet printing CIBA GEIGY AG (CH) 1995-02-08 CN disclosed
CN-1026592-C Ink for ink jet printing CIBA GEIGY AG (CH) 1994-11-16 CN disclosed
CN-1043517-A Ink for ink jet printing CIBA GEIGY AG (CH) 1990-07-04 CN disclosed