Phenol

Phenol

SCHEMBL454730

O=COc1cccc(O)c1.Oc1ccccc1.Oc1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.47
DRD2 P14416 1/20 0.44
DRD4 P21917 1/20 0.44
ADRA1D P25100 1/20 0.44
ADRA1A P35348 1/20 0.44
ADRA1B P35368 1/20 0.44
DRD3 P35462 1/20 0.44
CCNB2 O95067 1/20 0.43
CDK1 P06493 1/20 0.43
CDK4 P11802 1/20 0.43
CCNB1 P14635 1/20 0.43
CCND1 P24385 1/20 0.43
CCNB3 Q8WWL7 1/20 0.43
CA12 O43570 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 3/20 0.42
CA14 Q9ULX7 2/20 0.42
CA1 P00915 2/20 0.42
GLA P06280 1/20 0.42
CA3 P07451 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL359808 1.00 CYP3A4 (0.47) CYP3A4DRD2DRD4ADRA1DADRA1A
Phenol SCHEMBL28088385 1.00 CYP3A4 (0.47) CYP3A4DRD2DRD4ADRA1DADRA1A
Hydroquinone SCHEMBL3753752 0.94 CYP3A4 (0.48) CYP3A4CCNB2CDK1CDK4CCNB1
SCHEMBL320511 0.94 CYP3A4 (0.52) CYP3A4DRD2DRD4ADRA1DADRA1A
Biphenyl SCHEMBL27258263 0.93 HSD17B1 (0.45) CYP3A4DRD2DRD4ADRA1DADRA1A
Resorcinol SCHEMBL1715185 0.92 CYP3A4 (0.50) CYP3A4DRD2DRD4ADRA1DADRA1A
Charcoal, Activated SCHEMBL3483629 0.92 CYP3A4 (0.50) CYP3A4DRD2DRD4ADRA1DADRA1A
SCHEMBL4463825 0.92 CYP3A4 (0.50) CYP3A4DRD2DRD4ADRA1DADRA1A
SCHEMBL28290002 0.92 CYP3A4 (0.50) CYP3A4DRD2DRD4ADRA1DADRA1A
SCHEMBL28073121 0.92 CYP3A4 (0.50) CYP3A4DRD2DRD4ADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120064287-A1 AEROGEL COMPOSITE AND METHOD OF MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-03-15 US disclosed