Biphenyl

Biphenyl

SCHEMBL27258264

O=Cc1c(O)cccc1O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
ERN1 O75460 6/20 0.48
TRIM24 O15164 1/20 0.48
TRIM33 Q9UPN9 1/20 0.48
BCL2L1 Q07817 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PADI4 Q9UM07 1/20 0.43
MMP3 P08254 1/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
RECQL P46063 1/20 0.42
KMT2A Q03164 1/20 0.42
ALOX5 P09917 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL311198 0.88 ERN1 (0.54) ERN1TRIM24TRIM33ALDH1A1HPGD
Charcoal, Activated SCHEMBL29407959 0.85 ERN1 (0.52) ERN1TRIM24TRIM33ALDH1A1HPGD
SCHEMBL30541650 0.85 ERN1 (0.52) ERN1TRIM24TRIM33ALDH1A1HPGD
SCHEMBL30522433 0.85 ERN1 (0.52) ERN1TRIM24TRIM33ALDH1A1HPGD
SCHEMBL29220003 0.85 ERN1 (0.52) ERN1TRIM24TRIM33ALDH1A1HPGD
SCHEMBL3963384 0.85 ALDH1A1 (0.56) HDAC4HDAC2HDAC8ERN1TRIM24
Water SCHEMBL30515441 0.83 ERN1 (0.50) ERN1TRIM24TRIM33ALDH1A1HPGD
SCHEMBL30229858 0.78 ALDH1A1 (0.57) HDAC4HDAC2HDAC8ERN1TRIM24
Tert-Butylbenzene SCHEMBL27403806 0.78 HDAC4 (0.50) HDAC4HDAC2HDAC8ERN1TRIM24
Biphenyl SCHEMBL27595404 0.77 TRIM24 (0.82) HDAC4HDAC2HDAC8ERN1TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1098428-A The China ink that is used for ink-jet printing CIBA GEIGY AG (CH) 1995-02-08 CN disclosed
CN-1026592-C Ink for ink jet printing CIBA GEIGY AG (CH) 1994-11-16 CN disclosed
CN-1043517-A Ink for ink jet printing CIBA GEIGY AG (CH) 1990-07-04 CN disclosed