SCHEMBL27260507

SCHEMBL27260507

CC(C)[C@H](NC(=O)CNC(=O)CNC(=O)CN1CCN2CC(=O)OC3(CN4CCN5CC(=O)OC(C1)(C5)C3OC(=O)C4)C2)C(=O)N[C@H](C)C(=O)N1CCC[C@H]1B(O)O

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PREP P48147 14/20 0.37
▸ FAP Q12884 14/20 0.37
▸ DPP4 P27487 9/20 0.36
▸ DPP8 Q6V1X1 6/20 0.36
▸ DPP9 Q86TI2 6/20 0.36
▸ DPP7 Q9UHL4 6/20 0.32
▸ PITRM1 Q5JRX3 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27260613 0.92 PREP (0.32) PREPFAPDPP4DPP8DPP9
SCHEMBL27257649 0.88 FAP (0.42) PREPFAPDPP4DPP8DPP9
SCHEMBL25894973 0.88 PREP (0.43) PREPFAPDPP4DPP8DPP9
SCHEMBL25894997 0.88 PREP (0.43) PREPFAPDPP4DPP8DPP9
SCHEMBL25894584 0.88 PREP (0.43) PREPFAPDPP4DPP8DPP9
SCHEMBL27260074 0.88 FAP (0.45) PREPFAPDPP4DPP8DPP9
SCHEMBL27260368 0.87 PREP (0.44) PREPFAPDPP4DPP8DPP9
SCHEMBL27260123 0.85 PREP (0.39) PREPFAPDPP4DPP8DPP9
SCHEMBL27261547 0.83 FAP (0.39) PREPFAPDPP4DPP8DPP9
SCHEMBL27261360 0.83 FAP (0.39) PREPFAPDPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207292-A1 BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS TRUSTEES OF TUFTS COLLEGE 2024-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207292-A1 BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS BCL6B, BCL6, BTD PREP 2680/4885FAP 1959/4885DPP4 3953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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