Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 3/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | TGM1 | P22735 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27262201 | 0.91 | ALDH1A1 (0.56) | ALDH1A1TGFBR1NPC1MAPTMAPK1 | |
| SCHEMBL1673587 | 0.86 | ALDH1A1 (0.63) | ALDH1A1TGFBR1NPC1MAPTMAPK1 | |
| SCHEMBL29744615 | 0.86 | ALDH1A1 (0.63) | ALDH1A1TGFBR1NPC1MAPTMAPK1 | |
| SCHEMBL4117538 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TGFBR1NPC1MAPTMAPK1 | |
| SCHEMBL22605462 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TGFBR1NPC1MAPTMAPK1 | |
| SCHEMBL27262196 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TGFBR1NPC1MAPTMAPK1 | |
| SCHEMBL27262170 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TGFBR1NPC1MAPTMAPK1 | |
| SCHEMBL22588143 | 0.81 | ALDH1A1 (0.55) | ALDH1A1TGFBR1NPC1MAPTMAPK1 | |
| SCHEMBL30870644 | 0.81 | ALDH1A1 (0.55) | ALDH1A1TGFBR1NPC1MAPTMAPK1 | |
| SCHEMBL17376175 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TGFBR1NPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024064026-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-28 | — | — | WO | disclosed |