SCHEMBL27263102

SCHEMBL27263102

CC1(C)OB(c2ccc(Cl)c(-c3ccccc3)c2)OC1(C)C

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 11/20 0.60
LPL P06858 10/20 0.60
PDGFRB P09619 1/20 0.41
KDR P35968 1/20 0.41
CYP2A6 P11509 1/20 0.40
P4HB P07237 1/20 0.39
DGAT1 O75907 1/20 0.37
EGFR P00533 2/20 0.37
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
ROCK1 Q13464 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19533269 0.85 LIPG (0.66) LIPGLPLPDGFRBKDRP4HB
SCHEMBL29653625 0.85 LIPG (0.66) LIPGLPLPDGFRBKDRP4HB
SCHEMBL26546881 0.83 LIPG (0.62) LIPGLPLPDGFRBKDRP4HB
SCHEMBL16788914 0.83 LIPG (0.62) LIPGLPLPDGFRBKDRP4HB
SCHEMBL623701 0.83 LIPG (0.62) LIPGLPLPDGFRBKDRP4HB
SCHEMBL29871636 0.81 LIPG (0.60) LIPGLPLPDGFRBKDRP4HB
SCHEMBL759136 0.81 LIPG (0.60) LIPGLPLPDGFRBKDRP4HB
SCHEMBL28470742 0.81 LIPG (0.60) LIPGLPLPDGFRBKDRP4HB
SCHEMBL30999401 0.80 LIPG (0.68) LIPGLPLPDGFRBKDRP4HB
SCHEMBL30919878 0.80 LIPG (0.50) LIPGLPLCYP2A6EGFRPRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4618755-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2025-09-24 EP disclosed
WO-2024107746-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES (US) 2024-05-23 WO disclosed
WO-2024107746-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES (US) 2024-05-23 WO disclosed