SCHEMBL27263274

SCHEMBL27263274

COc1ccc(B2OC(C)(C)C(C)(C)O2)cc1-c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 9/20 0.57
LPL P06858 8/20 0.57
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
CSF1R P07333 1/20 0.42
PDGFRB P09619 1/20 0.40
KDR P35968 1/20 0.40
PGR P06401 1/20 0.40
SNCA P37840 1/20 0.38
DGAT1 O75907 1/20 0.38
NPC1 O15118 1/20 0.37
TSHR P16473 1/20 0.37
RAB9A P51151 1/20 0.37
P4HB P07237 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22678624 0.83 LIPG (0.51) LIPGLPLCSF1RPDGFRBKDR
SCHEMBL19533269 0.83 LIPG (0.66) LIPGLPLPDGFRBKDRDGAT1
SCHEMBL29653625 0.83 LIPG (0.66) LIPGLPLPDGFRBKDRDGAT1
SCHEMBL5793212 0.82 LIPG (0.60) LIPGLPLSNCADGAT1P4HB
SCHEMBL26546881 0.80 LIPG (0.62) LIPGLPLPDGFRBKDRDGAT1
SCHEMBL16788914 0.80 LIPG (0.62) LIPGLPLPDGFRBKDRDGAT1
SCHEMBL30957391 0.80 CSF1R (0.40) LIPGLPLCSF1RPDGFRBKDR
SCHEMBL25203373 0.79 CSF1R (0.48) LIPGLPLCSF1RSNCA
SCHEMBL1877988 0.79 CSF1R (0.48) LIPGLPLCSF1RSNCA
SCHEMBL759136 0.79 LIPG (0.60) LIPGLPLMAOAMAOBPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4618755-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2025-09-24 EP disclosed
WO-2024107746-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES (US) 2024-05-23 WO disclosed
WO-2024107746-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES (US) 2024-05-23 WO disclosed