Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3887001 | 0.84 | ALDH1A1 (0.45) | DDB1CRBNSIGMAR1ALDH1A1CYP2C19 | |
| SCHEMBL29845330 | 0.84 | ALDH1A1 (0.45) | DDB1CRBNSIGMAR1ALDH1A1CYP2C19 | |
| SCHEMBL25213325 | 0.83 | ALDH1A1 (0.46) | DDB1CRBNALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL30843298 | 0.83 | DDB1 (0.47) | DDB1CRBNSIGMAR1ALDH1A1CYP2C19 | |
| Hydrochloric Acid SCHEMBL6543327 | 0.83 | ALDH1A1 (0.44) | DDB1CRBNSIGMAR1ALDH1A1CYP2C19 | |
| SCHEMBL10919547 | 0.81 | DDB1 (0.45) | DDB1CRBNALDH1A1KDM4E | |
| SCHEMBL12987543 | 0.79 | KMT2A (0.42) | KDM4E | |
| SCHEMBL12987567 | 0.79 | KMT2A (0.42) | KDM4E | |
| SCHEMBL14858081 | 0.79 | KMT2A (0.42) | KDM4E | |
| SCHEMBL14858626 | 0.79 | KMT2A (0.42) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1024668-C | Preparation method of 2- (2-isoxazolidinyl) -2-tetrahydrofuran carboxylic acid derivative | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-05-25 | — | — | CN | disclosed |
| CN-85109633-A | Process for the preparation of antibiotic derivatives | — | 1987-01-07 | — | — | CN | disclosed |