Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27264691 | 1.00 | CPN1 (0.40) | CPN1CPB2CTSBTBXAS1F10 | |
| SCHEMBL31626139 | 1.00 | CPN1 (0.40) | CPN1CPB2CTSBTBXAS1F10 | |
| SCHEMBL31626012 | 1.00 | CPN1 (0.40) | CPN1CPB2CTSBTBXAS1F10 | |
| SCHEMBL31626010 | 0.99 | CPN1 (0.41) | CPN1CPB2CTSBTBXAS1F10 | |
| SCHEMBL27264682 | 0.99 | CPN1 (0.41) | CPN1CPB2CTSBTBXAS1F10 | |
| SCHEMBL27264382 | 0.94 | CPN1 (0.42) | CPN1CPB2CTSBTBXAS1F10 | |
| SCHEMBL31626107 | 0.90 | CTSB (0.41) | CPN1CPB2CTSBF10CTSL | |
| SCHEMBL27264689 | 0.90 | CTSB (0.41) | CPN1CPB2CTSBF10CTSL | |
| SCHEMBL31626106 | 0.86 | CTSB (0.35) | CPN1CPB2CTSBCTSLCTSS | |
| SCHEMBL30805312 | 0.86 | CTSB (0.35) | CPN1CPB2CTSBCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054845-A1 | MACROCYCIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |