Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732863 | 0.95 | HSD17B10 (0.52) | HSD17B10ALOX15MAPK1HSPA1APABPC1 | |
| SCHEMBL31415633 | 0.75 | KCNH2 (0.46) | HSD17B10ALOX15CYSLTR2CYSLTR1CYP3A4 | |
| SCHEMBL2810677 | 0.75 | KCNH2 (0.46) | HSD17B10ALOX15CYSLTR2CYSLTR1CYP3A4 | |
| SCHEMBL2726989 | 0.75 | HSPA1A (0.54) | HSD17B10ALOX15MAPK1HSPA1APABPC1 | |
| SCHEMBL5085494 | 0.73 | KCNH2 (0.43) | HSD17B10ALOX15CYSLTR2CYSLTR1CYP3A4 | |
| SCHEMBL23276782 | 0.73 | STAT3 (0.59) | TSHRALDH1A1TDP1CYP1A2 | |
| SCHEMBL23276488 | 0.73 | STAT3 (0.59) | TSHRALDH1A1TDP1CYP1A2 | |
| SCHEMBL6371432 | 0.72 | KCNH2 (0.58) | HSD17B10ALOX15CYSLTR2CYSLTR1CYP3A4 | |
| SCHEMBL7675911 | 0.72 | HSPA1A (0.54) | HSD17B10ALOX15MAPK1HSPA1APABPC1 | |
| SCHEMBL23276401 | 0.71 | STAT3 (0.60) | TSHRALDH1A1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630115-B1 | Crosslinking monomers for aliphatic polyamides | NEXAM CHEMICAL AB (SE) | 2014-05-14 | — | — | EP | claimed |
| US-20130225769-A1 | CROSS-LINKER | NEXAM CHEMICAL AB (SE) | 2013-08-29 | — | — | US | claimed |
| US-20140303328-A1 | CROSS-LINKER | NEXAM CHEMICAL AB (SE) | 2014-10-09 | — | — | US | disclosed |
| US-8772418-B2 | Cross-linker | NEXAM CHEMICAL AB (SE) | 2014-07-08 | — | — | US | disclosed |
| EP-2630115-B1 | Crosslinking monomers for aliphatic polyamides | NEXAM CHEMICAL AB (SE) | 2014-05-14 | — | — | EP | disclosed |
| US-20130225769-A1 | CROSS-LINKER | NEXAM CHEMICAL AB (SE) | 2013-08-29 | — | — | US | disclosed |
| EP-2630115-A1 | CROSS-LINKER | Nexam Chemical AB (SE) | 2013-08-28 | — | — | EP | disclosed |
| WO-2012052550-A1 | CROSS-LINKER | NEXAM CHEMICAL AB (SE) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303328-A1 | CROSS-LINKER | CAPZA2, PAPSS1, CHIA | HSD17B10 3154/4885ALOX15 3582/4885MAPK1 4813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.