Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | KAT7 | O95251 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27265459 | 0.87 | USP30 (0.42) | USP30SRCEGFRHPGDSPIK3CA | |
| SCHEMBL30837097 | 0.85 | PIK3CA (0.40) | USP30SRCEGFRHPGDSPIK3CA | |
| SCHEMBL30837093 | 0.85 | PIK3CA (0.40) | USP30SRCEGFRHPGDSPIK3CA | |
| SCHEMBL30837094 | 0.85 | PIK3CA (0.40) | USP30SRCEGFRHPGDSPIK3CA | |
| SCHEMBL30837026 | 0.85 | PIK3CA (0.40) | USP30SRCEGFRHPGDSPIK3CA | |
| SCHEMBL19499693 | 0.84 | FGFR1 (0.47) | — | |
| SCHEMBL17119658 | 0.83 | SRC (0.47) | USP30SRCEGFRHPGDSPIK3CA | |
| SCHEMBL16415065 | 0.82 | GPR119 (0.46) | GPR119 | |
| SCHEMBL19499700 | 0.80 | FGFR1 (0.47) | — | |
| SCHEMBL16246157 | 0.79 | FGFR1 (0.49) | SRCKAT7KAT8TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073745-A1 | INHIBITORS OF EGFR OR HER2 AND METHODS OF USE | ARBELLA THERAPEUTICS, LLC (US) | 2024-04-04 | — | — | WO | disclosed |