Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3165932 | 0.87 | DPP7 (0.82) | DPP7KMT2ASIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL3171554 | 0.85 | DPP7 (0.79) | DPP7KMT2ASIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL3176696 | 0.80 | DPP7 (0.72) | DPP7KMT2ASIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL14385453 | 0.79 | DPP7 (0.70) | DPP7KMT2ASIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL18769662 | 0.79 | DPP7 (0.70) | DPP7KMT2ASIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL3175086 | 0.79 | DPP7 (0.70) | DPP7KMT2ASIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL3577555 | 0.79 | DPP7 (0.70) | DPP7KMT2ASIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL2554982 | 0.78 | HRH3 (0.61) | SIGMAR1CYP3A4 | |
| SCHEMBL5756091 | 0.78 | DPP7 (1.00) | DPP7KMT2ASIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL23686821 | 0.78 | DPP7 (0.68) | DPP7KMT2ASIGMAR1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026026-A1 | HIGH THROUGHPUT IN VIVO SCREENING OF LIPID NANOPARTICLES | TRUSTEES OF TUFTS COLLEGE (US) | 2024-02-01 | — | — | WO | disclosed |