SCHEMBL5756091

SCHEMBL5756091

c1ccc(CNCCN2CCCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 1.00
SIGMAR1 Q99720 3/20 0.72
SLC6A3 Q01959 1/20 0.58
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
DRD3 P35462 1/20 0.54
APP P05067 1/20 0.53
MAOA P21397 1/20 0.52
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5754930 0.98 DPP7 (0.96) DPP7SIGMAR1SLC6A3KMT2AMEN1
SCHEMBL8883456 0.98 DPP7 (0.96) DPP7SIGMAR1SLC6A3KMT2AMEN1
Hydrochloric Acid SCHEMBL5758454 0.96 DPP7 (0.93) DPP7SIGMAR1SLC6A3KMT2AMEN1
Hydrochloric Acid SCHEMBL5759171 0.96 DPP7 (0.93) DPP7SIGMAR1SLC6A3KMT2AMEN1
SCHEMBL3165932 0.90 DPP7 (0.82) DPP7SIGMAR1KMT2AAPPCYP3A4
SCHEMBL3171554 0.89 DPP7 (0.79) DPP7SIGMAR1KMT2AAPPCYP3A4
Hydrochloric Acid SCHEMBL10606789 0.86 DPP7 (0.76) DPP7SIGMAR1SLC6A3MAOACYP3A4
SCHEMBL39631 0.84 DPP7 (0.73) DPP7SIGMAR1KMT2AMEN1TDP1
SCHEMBL9048454 0.84 DPP7 (0.73) DPP7SIGMAR1KMT2AMEN1TDP1
SCHEMBL9019137 0.84 SIGMAR1 (1.00) DPP7SIGMAR1SLC6A3DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691136-B2 Olefin oligomerization catalyst and method for producing olefin oligomer in the presence of the same catalyst MITSUI CHEMICALS, INC. (JP) 2023-07-04 US disclosed
US-11691136-B2 Olefin oligomerization catalyst and method for producing olefin oligomer in the presence of the same catalyst MITSUI CHEMICALS, INC. (JP) 2023-07-04 US disclosed
US-20200222886-A1 OLEFIN OLIGOMERIZATION CATALYST AND METHOD FOR PRODUCING OLEFIN OLIGOMER IN THE PRESENCE OF THE SAME CATALYST MITSUI CHEMICALS, INC. (JP) 2020-07-16 US disclosed
US-9920010-B2 CXCR7 receptor modulators IDORSIA PHARMACEUTICALS LTD (CH) 2018-03-20 US disclosed
EP-3004082-B1 CXCR7 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2017-08-02 EP disclosed
US-20160107997-A1 CXCR7 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2016-04-21 US disclosed
EP-3004082-A1 CXCR7 RECEPTOR MODULATORS Actelion Pharmaceuticals Ltd. (CH) 2016-04-13 EP disclosed
WO-2014191929-A1 CXCR7 RECEPTOR MODULATORS ACTELION PHARMACEUTICALS LTD (CH) 2014-12-04 WO disclosed
EP-1401821-A4 NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS SK CORP (KR) 2006-05-31 EP disclosed
EP-1401821-A1 NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS SK Corporation (KR) 2004-03-31 EP disclosed
WO-2002100848-A1 NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS SK CORPORATION (KR) 2002-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160107997-A1 CXCR7 RECEPTOR MODULATORS CXCR1, CXCR5, CXCR2 DPP7 1861/4885SIGMAR1 166/4885SLC6A3 1418/4885
US-20200222886-A1 OLEFIN OLIGOMERIZATION CATALYST AND METHOD FOR PRODUCING OLEFIN OLIGOMER IN THE PRESENCE OF THE SAME CATALYST OXER1, COG6, CBR1 DPP7 4684/4885SIGMAR1 505/4885SLC6A3 4426/4885
US-11691136-B2 Olefin oligomerization catalyst and method for producing olefin oligomer in the presence of the same catalyst OXER1, COG6, CBR1 DPP7 4684/4885SIGMAR1 505/4885SLC6A3 4426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.