Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27355069 | 0.87 | KMT2A (0.57) | PPARGKMT2ALMNAPPARAACACB | |
| SCHEMBL18067342 | 0.85 | KMT2A (0.55) | PPARGKMT2ALMNAPPARAACACB | |
| SCHEMBL23917908 | 0.80 | KMT2A (0.47) | PPARGKMT2ALMNAPPARAACACB | |
| SCHEMBL14898375 | 0.79 | KMT2A (0.50) | KMT2AACACBTDP1MEN1ALDH1A1 | |
| SCHEMBL27355068 | 0.78 | KMT2A (0.53) | PPARGKMT2ALMNAPPARAACACB | |
| SCHEMBL18356896 | 0.76 | PPARG (0.48) | PPARGLMNAPPARAALDH1A1HPGD | |
| SCHEMBL20976935 | 0.76 | PPARG (0.48) | PPARGLMNAPPARAALDH1A1HPGD | |
| SCHEMBL15075296 | 0.76 | PPARG (0.48) | PPARGLMNAPPARAALDH1A1HPGD | |
| SCHEMBL4943113 | 0.75 | GNPAT (0.49) | PPARGKMT2ALMNAPPARAACACB | |
| SCHEMBL23917936 | 0.75 | KMT2A (0.48) | PPARGKMT2ALMNAPPARAACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006272-A1 | β-GLUCURONIDE LINKER-PAYLOADS, PROTEIN CONJUGATES THEREOF, AND METHODS THEREOF | SUTRO BIOPHARMA, INC. (US) | 2024-01-04 | — | — | WO | disclosed |